반응 #367493

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3-chlorophenylglyoxal

2-(4-methylphenyl)ethanamine

→

title compound

N-(2-(4-Methylphenyl)ethyl)-2-hydroxy-2-(3-chlorophenyl)ethanamine

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후처리

1. 1
   기타The title compound was prepared in the manner
2. 2
   기타Recrystallization of the chromatographed material from cyclohexane

실험 절차

The title compound was prepared in the manner described in Example 9 using 3-chlorophenylglyoxal and 2-(4-methylphenyl)ethanamine. Recrystallization of the chromatographed material from cyclohexane gave the title compound m.p. 85-88 (analysed as the hemi-hydrate). τ(CDCl3) 7.7 (3H, s), 7.0-7.5 (6H, m, +2H disappears with D2O), 5.4 (1H, dd), 2.9 (4H, s), 2.6-2.8 (4H, m).

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