반응 #367197

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2,4-diamino-5-(3-hydroxy-4,5-dimethoxybenzyl)pyrimidine

propargyl chloride

→

title compound

2,4-Diamino-5-[3,4-dimethoxy-5-(2-propynyloxy)benzyl]pyrimidine

반응 조건

후처리

1. 1
   기타Recrystallization from 95% ethanol

실험 절차

The title compound was prepared from 2,4-diamino-5-(3-hydroxy-4,5-dimethoxybenzyl)pyrimidine and propargyl chloride by the procedure of Example 1A. Recrystallization from 95% ethanol gave off-white needles (73%); mp 160°-161°. Anal. Calcd for C16H18N4O3 : C, 61.13; H, 5.77; N, 17.82. Found: C, 60.96; H, 5.80; N, 17.75.

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