반응 #366971

반응 방정식

dicyanoglutarate

2,4-dicyanoglutaric acid diethyl ester

polyoxymethylene

sodium methylate

sodium methylate

→

2-cyanoacrylic acid ethyl ester

수율 59.6%

용매

water

반응 조건

후처리

1. 1
   기타The water present was then removed

실험 절차

494.0 g (2.074 moles) of 2,4-dicyanoglutaric acid diethyl ester were reacted in the absence of water with 44.8 g of polyoxymethylene (92%; 1.372 moles) and 3 g of a 30% solution of sodium methylate in methanol (0.0167 mole). The quantity of sodium methylate used corresponded to an excess of 1.25 millimoles per mole of dicyanoglutarate. The reaction was carried out over a period of 45 minutes at a temperature of 100° C.-130° C. The water present was then removed using an oil pump vacuum. Thermolysis produced 154.5 g (1.236 moles) of 2-cyanoacrylic acid ethyl ester after distillation. The yield thus amounted to 31.3% by weight, based on 2,4-dicyanoglutarate.

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