반응 #364153

반응 방정식

5-methylsalicylaldehyde

malonic acid

pyridine

aniline

→

6-methyl-2-oxo-2H-1-benzopyran-3-carboxylic acid

용매

water

ethanol

반응 조건

후처리

1. 1
   추출extracted with ether
2. 2
   기타The solvent is removed by distillation under reduced pressure
3. 3
   기타The residue obtained
4. 4
   기타is recrystallized from ethanol

실험 절차

2 g of 5-methylsalicylaldehyde (14.7 mmol), 3.06 g of malonic acid (29.4 mmol), 1.3 g of pyridine and 0.08 g of aniline are dissolved in a minimum amount of ethanol. The mixture is heated at 40° C. on a water bath for 6 h. Next, it is diluted with water, acidified and then extracted with ether. The solvent is removed by distillation under reduced pressure. The residue obtained is recrystallized from ethanol.

출처