반응 #363771

반응 방정식

thiazolidine

2-(4-cyano-2-ethylphenylimino)-3-thia-1-azaspiro[4.4]nonane

3-bromopentane

→

2-(4-cyano-2-ethylphenylimino)-1-(3-pentyl)-3-thia-1-azaspiro[4.4]nonane

반응 조건

실험 절차

1-Hydroxymethylcyclopentanamine was prepared according to Method B1c. The 2-hydroxyethylamine was converted to 1-chloromethylcyclopentanamine HCl salt according to Method B7e. 1-Chloromethylcyclopentanamine HCl salt was reacted with 4-cyano-2-ethylphenyl isothiocyanate according to Method C1e to give 2-(4-cyano-2-ethylphenylimino)-3-thia-1-azaspiro[4.4]nonane. The thiazolidine was reacted with 3-bromopentane according to Method D2b to give 2-(4-cyano-2-ethylphenylimino)-1-(3-pentyl)-3-thia-1-azaspiro[4.4]nonane.

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