반응 #361944
ord-657abbb53a14432ebc0bf161407cc8a6
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타The solvent was removed in vacuo
- 2세척the solid washed repeatedly with water
- 3여과collected by filtration
- 4기타dried
실험 절차
To a suspension of 1-hydroxy-2-naphthoic acid (2.5 g; 13.3 mm) in chloroform (50 ml) was added bromine (0.68 ml) in chloroform (5 ml) dropwise and the reaction stirred at room temperature for one hour. The solvent was removed in vacuo, the solid washed repeatedly with water and collected by filtration and dried to give 4-bromo-1-hydroxy-naphthalene-2-carboxylic acid as a white solid.