반응 #357204

반응 방정식

solution

tert-butyl 4-(4-fluorophenyl)-3,6-dihydropyridine-1(2H)-carboxylate

HCl

→

desired product

수율 141.1%

4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine

수율 141.1%

용매

dichloromethane

diethyl ether

반응 조건

후처리

1. 1
   농축concentrated

실험 절차

A solution of Example 6B (0.5 g, 1.8 mmol) in dichloromethane (5 mL) at room temperature was treated with 2M HCl in diethyl ether (5 mL), stirred overnight, and concentrated to provide the desired product (0.45 g, 95%). MS (ESI) m/e 178 (M+H)+.

출처