반응 #3572

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6-(2-bromo-6-chloro-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

6-(2-Bromo-6-chloro-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

tert-butyl isocyanate

→

title compound

1-[2-Amino-6-(2-bromo-6-chloro-phenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butyl-urea

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후처리

1. 1
   기타The product was purified by MPLC
2. 2
   세척eluting with 1:1CHCl3

실험 절차

The title compound was prepared using 0.30 g of 6-(2-bromo-6-chloro-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine from Example 104 and 0.105 mL of tert-butyl isocyanate according to Example 2. The product was purified by MPLC eluting with 1:1CHCl3 :EtOAc; mp 314° C. (dec); MS(CI).

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