반응 #3561

반응 방정식

6-(2,3-dimethyl-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

6-(2,3-Dimethyl-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

tert-butyl isocyanate

→

title compound

1-[2-Amino-6-(2,3-dimethyl-phenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butyl-urea

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후처리

1. 1
   기타The product was purified by MPLC
2. 2
   세척eluting with a gradient of CHCl3 :EtOAc (2:1) to CHCl3 :EtOAc (1:1)

실험 절차

The title compound was prepared from 0.5007 g of 6-(2,3-dimethyl-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine from Example 92 and 0.23 mL tert-butyl isocyanate according to Example 2. The product was purified by MPLC eluting with a gradient of CHCl3 :EtOAc (2:1) to CHCl3 :EtOAc (1:1); mp 326°-330° C., MS(CI).

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