반응 #353300

반응 방정식

sulfuric acid

2-amino-4,5,3',4'-tetramethoxybenzophenone

butyl acetoacetate

→

butyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylquinoline-3-carboxylate

수율 53.0%

용매

acetic acid

반응 조건

후처리

1. 1
   workup.ADDITIONThe mixture was treated

실험 절차

Conc. sulfuric acid was added to a mixture of 2-amino-4,5,3',4'-tetramethoxybenzophenone, butyl acetoacetate and acetic acid. The mixture was treated according to the same manner as in Reference Example 1 to give butyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-methylquinoline-3-carboxylate (53%). This compound was recrystallized from ethyl acetatehexane. Colorless prisms, mp. 119°-120° C.

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