반응 #350559

ord-8bef3a7975ed42dc885d5b77b6c6816b

반응 방정식

CCCC(O)CC(=O)O
3-hydroxy hexanoic acid
CCC[C@@H](O)CC(=O)O
(R)-3-hydroxyhexanoic acid
CCC[C@H](O)CC(=O)O
(S)-3-hydroxyhexanoic acid

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The reaction times
  2. 2
    기타The conversion of 20-80% is attained within the above preferable reaction times

실험 절차

The reaction times are suitably 1 to 1000 hours, preferably 1 to 200 hours. Namely, the reaction time depends on the kind of the racemic esters of 3-hydroxy hexanoic acid which are starting materials. The conversion of 20-80% is attained within the above preferable reaction times. In this case, in the reaction of the conversion of 50% or less, (R)-3-hydroxyhexanoic acid having optical purity over 90% ee is obtained, while in the reaction of the conversion of 50% or more, (S)-3-hydroxyhexanoic acid having optical purity over 90% ee is obtained.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05643793uspto-grants-1997_07