반응 #349099

반응 방정식

thionyl chloride

cyclopentaneacetic acid

thionyl chloride

→

cyclopentylacetyl chloride

용매

N,N-dimethylformamide

반응 조건

후처리

1. 1
   기타is removed in vacuo
2. 2
   workup.DISTILLATIONthe residual oil is distilled
3. 3
   기타to give 55.4 g

실험 절차

To a solution of 50 g. of cyclopentaneacetic acid containing 2.9 ml of N,N-dimethylformamide is added dropwise with stirring, 51 g. of thionyl chloride over a period of 15 minutes. After stirring for an additional 60 minutes excess thionyl chloride is removed in vacuo and the residual oil is distilled to give 55.4 g. (97%) of product, b.p. 57°-58° C. (10 mm.).

출처