반응 #348956

반응 방정식

1,3-diphenyl-2-propanone

tris(formylamino)methane

dimethylformamide

→

3,5-diphenyl-4(1H)-pyridone

용매

water

반응 조건

후처리

1. 1
   온도at reflux temperature for 3 hours
2. 2
   온도The mixture was then cooled to approximately room temperature
3. 3
   기타The precipitated solids were separated by filtration
4. 4
   여과The chloroform was then filtered
5. 5
   세척the solids remaining were washed first with water

실험 절차

A 1.4 g. portion of 1,3-diphenyl-2-propanone was mixed with 1.0 g. of tris(formylamino)methane in 20 ml. of dimethylformamide. The reaction mixture was stirred at reflux temperature for 3 hours. The mixture was then cooled to approximately room temperature, and poured into water. The precipitated solids were separated by filtration, and the solids were suspended in chloroform. The chloroform was then filtered, and the solids remaining were washed first with water, and then with chloroform. The yield was about 100 mg. of 3,5-diphenyl-4(1H)-pyridone, m.p. greater than 335° C.

출처