반응 #347056

반응 방정식

norbornene

trichlorosilane

→

(1S, 2S, 4R)-2-trichlorosilylnorbornane

수율 96.8%

용매

toluene

반응 조건

후처리

1. 1
   기타Thereafter, from the reaction mixture, the solvent was evaporated off at 100° C. under reduced pressure of 1 Torr

실험 절차

(R)-2-Methoxy-2'-di(4-chlorophenyl)phosphino-1,1'-binaphthyl prepared in Example 3 (7.93 mg, 14.78 mmol) and allylpalladium chloride dimer (1.35 mg, 3.69 μmol=7.38 μmol of palladium) were dissolved in toluene (6.95 g). In the solution, norbornene (6.95 g, 73.81 mmol) was added. After adding trichlorosilane (12.00 g, 88.59 mmol) at 0° C., the mixture was warmed to room temperature, followed by stirring at room temperature for 12 hours. Thereafter, from the reaction mixture, the solvent was evaporated off at 100° C. under reduced pressure of 1 Torr to obtain (1S, 2S, 4R)-2-trichlorosilylnorbornane (16.41 g). Isolation yield, 97%.

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