반응 #346247

반응 방정식

1-decanol

mesyl chloride

→

decyl methylsulfonate

용매

n-hexane

collidine

반응 조건

후처리

1. 1
   workup.ADDITIONpoured onto ice
2. 2
   추출The reaction mixture is extracted with ether
3. 3
   세척the ether extracts are washed with 10% hydrochloric acid
4. 4
   건조dried over anhydrous sodium sulfate
5. 5
   기타the solvent removed under reduced pressure
6. 6
   기타to leave an oil which
7. 7
   온도upon cooling
8. 8
   온도cooled

실험 절차

To a cooled solution of 158.3 grams of 1-decanol in 1.0 liter of collidine is added dropwise 126 grams of mesyl chloride. The resulting mixture is stirred at room temperature for 1.5 hours and then poured onto ice. The reaction mixture is extracted with ether and the ether extracts are washed with 10% hydrochloric acid. The ether extracts are combined, dried over anhydrous sodium sulfate, and the solvent removed under reduced pressure to leave an oil which solidifies upon cooling. The oil is dissolved in n-hexane and cooled to yield as crystals, decyl methylsulfonate.

출처