반응 #344036

반응 방정식

rac-3,4-dihydro-2-ethynyl-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol

1-iodonaphthalene

→

rac-3,4-dihydro-2,5,7,8-tetramethyl-2-[(1-naphthyl)ethynyl]-2H-1-benzopyran-6-ol

용매

methylene chloride

반응 조건

후처리

1. 1
   기타It was isolated by chromatography over 40 fold amount of silica gel
2. 2
   기타The combined clean fractions were crystallized from hexane
3. 3
   기타recrystallized from petroleum ether
4. 4
   기타to give colorless crystals with m.p. 127°-128°

실험 절차

rac-3,4-dihydro-2,5,7,8-tetramethyl-2-[(1-naphthyl)ethynyl]-2H-1-benzopyran-6-ol was prepared by coupling rac-3,4-dihydro-2-ethynyl-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol with 1-iodonaphthalene under the conditions described in Example 1. It was isolated by chromatography over 40 fold amount of silica gel using methylene chloride. The combined clean fractions were crystallized from hexane and recrystallized from petroleum ether to give colorless crystals with m.p. 127°-128°.

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