반응 #343980

반응 방정식

2-hydroxyoctanoic acid

decyl alcohol

→

clear pale yellow liquid

수율 77.3%

Decyl 2-Hydroxyoctanoate

수율 77.3%

용매

반응 조건

후처리

1. 1
   온도The mixture was heated to 140° for 8 hours
2. 2
   기타water was collected as the reaction
3. 3
   세척by washing three times with 50 ml saturated sodium bicarbonate solution
4. 4
   기타The organic layer was collected
5. 5
   건조dried over magnesium sulfate
6. 6
   기타Excess decyl alcohol was removed by high vacuum distillation

실험 절차

A 250 ml one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen inlet/outlet was charged with 20.0 g (0.125 moles) 2-hydroxyoctanoic acid, 79.0 g (0.499 moles) decyl alcohol, and 0.062 g sulfuric acid. The mixture was heated to 140° for 8 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. Approximately 50 ml ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Excess decyl alcohol was removed by high vacuum distillation to yield 28.99 g (77.3% yield) of clear pale yellow liquid. According to GC the product is 99.6% pure.

출처