반응 #343976

반응 방정식

methyl lactate

decyl alcohol

NaOH

→

crude mixture

수율 180.9%

Decyl Lactate

수율 180.9%

용매

methanol

반응 조건

후처리

1. 1
   기타A 250 mL round bottom flask equipped with a spin bar
2. 2
   workup.DISTILLATIONa distillation column
3. 3
   추출extracted with ether
4. 4
   건조The organic layer was dried over MgSO4
5. 5
   여과filtered
6. 6
   기타dried in vacuo

실험 절차

A 250 mL round bottom flask equipped with a spin bar and a distillation column was charged with 100 g (0.96 moles) of methyl lactate, 304.1 g (1.92 moles) of decyl alcohol, and 500 mg of H2SO4. The reaction was heated until methanol formation ceased. The reaction was then neutralized with 0.1N NaOH (100 mL) and extracted with ether. The organic layer was dried over MgSO4, filtered and dried in vacuo to give 400 g of crude mixture. The fractional distillation was carried out three times to give 98.5 g (45% yield, 100% pure by GC) of a clear colorless oil.

출처