반응 #341797

반응 방정식

tromethamine

hydrochloric acid

citric acid anhydrous

sodium hydroxide

hydrochloric acid

sodium hydroxide

sodium hydroxide

trolamine

capric acid

capric acid

→

Capric Acid Lauric Acid

용매

water

water

반응 조건

후처리

1. 1
   workup.ADDITIONWe added the appropriate amount (
2. 2
   workup.ADDITIONmixed well
3. 3
   workup.DISSOLUTIONuntil dissolved
4. 4
   기타to 21-25° C.
5. 5
   기타(or room temperature)
6. 6
   기타to 45-50° C.
7. 7
   온도by warming on a hotplate
8. 8
   온도maintained this temperature
9. 9
   workup.DISSOLUTIONwas dissolved
10. 10
    기타to 21-25° C.
11. 11
    기타(or room temperature)
12. 12
    workup.ADDITIONWe then mixed the solution for 5 minutes
13. 13
    workup.ADDITIONmixed well

실험 절차

We transferred approximately 60% of the required sterile water volume into a suitable container. We added the appropriate amount (as indicated in the table below) of tromethamine, trolamine, citric acid anhydrous, and sodium hydroxide pellets to the container and mixed well until dissolved. We adjusted the temperature to 21-25° C. (or room temperature) and measured the pH of the liquid. We adjusted the pH to 7.7-7.9 as necessary using 1N sodium hydroxide or 1N hydrochloric acid. We then adjusted the temperature to 45-50° C. by warming on a hotplate and maintained this temperature. We then added the capric acid to the warm solution and mixed until the capric acid was dissolved. We adjusted the temperature to 21-25° C. (or room temperature) and measured the pH of the liquid. As needed, we adjusted the pH to 7.7-7.9 using 1N sodium hydroxide or 1N hydrochloric acid. We then mixed the solution for 5 minutes. We added appropriate amount of sterile water to equal 100% of the required volume and mixed well.

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