반응 #341069

ord-98b0aa28240a464da8341b33eadd1aff

반응 방정식

CCOC(=O)C(C)Sc1cnc(NC(=O)N(C2CCCCCC2)C2CCC2)s1
[2-(3-Cycloheptyl-3-cyclobutyl-ureido)-thiazol-5-ylsulfanyl]-propionic acid ethyl ester
C1CCCC(NC2CCC2)CC1
cycloheptyl-cyclobutylamine
CCOC(=O)CS.Nc1cncs1
5-aminothiazole 2-mercaptoacetic acid ethyl ester
O=C(O)CCSc1cnc(NC(=O)N(C2CCCCCC2)C2CCC2)s1
title compound
O=C(O)CCSc1cnc(NC(=O)N(C2CCCCCC2)C2CCC2)s1
3-[2-(3-Cyclobutyl-3-cycloheptyl-ureido)-thiazol-5-ylsulfanyl]-propionic acid

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타Hydrolysis

실험 절차

[2-(3-Cycloheptyl-3-cyclobutyl-ureido)-thiazol-5-ylsulfanyl]-propionic acid ethyl ester prepared as described in general procedure (A) using cycloheptyl-cyclobutylamine and 5-aminothiazole-2-mercaptoacetic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07872139B2uspto-grants-2011_01