반응 #341066

ord-42b9cc591fa84ee6b226a1eb30b42aeb

반응 방정식

CCOC(=O)CS.Nc1cncs1
5-aminothiazole 2-mercaptoacetic acid ethyl ester
CCOC(=O)CSc1cnc(NC(=O)N(C2CCCCCC2)C2CCCC2)s1
[2-(3-Cycloheptyl-3-cyclopentyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid ethyl ester
C1CCCC(NC2CCCC2)CC1
cycloheptyl-cyclopentylamine
O=C(O)CSc1cnc(NC(=O)N(C2CCCCCC2)C2CCCC2)s1
title compound
O=C(O)CSc1cnc(NC(=O)N(C2CCCCCC2)C2CCCC2)s1
[2-(3-Cycloheptyl-3-cyclopentyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타Hydrolysis

실험 절차

[2-(3-Cycloheptyl-3-cyclopentyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid ethyl ester prepared as described in general procedures (A) and (B) using cycloheptyl-cyclopentylamine and 5-aminothiazole-2-mercaptoacetic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07872139B2uspto-grants-2011_01