반응 #339612

반응 방정식

4-bromo-biphenyl

Chlorosulfonic acid

→

4′-bromo-biphenyl-4-sulfonic acid

수율 92.0%

용매

chloroform

반응 조건

후처리

1. 1
   기타A 500 mL round-bottom-flask equipped with an addition funnel
2. 2
   기타then purged with nitrogen
3. 3
   workup.STIRRINGthen stirred for 1 hour
4. 4
   여과The resulting precipitate was collected by vacuum filtration
5. 5
   세척washed with cold chloroform
6. 6
   기타dried under vacuum

실험 절차

A 500 mL round-bottom-flask equipped with an addition funnel, stirring bar, and gas inlet was charged with 4-bromo-biphenyl (50 g, 0.215 mol) and chloroform (200 mL) then purged with nitrogen. Chlorosulfonic acid (18 mL, 0.27 mol) was added dropwise to the solution from the addition funnel then stirred for 1 hour. The resulting precipitate was collected by vacuum filtration, washed with cold chloroform, and dried under vacuum to give 61.97 g of 4′-bromo-biphenyl-4-sulfonic acid (92% yield).

출처