반응 #339447

반응 방정식

2-bromo-3-methylthiophene

2-fluoro-5-pyridine-boronic acid

→

desired compound

수율 75.9%

2-Fluoro-5-(3-methyl-thiophen-2-yl)-pyridine

수율 75.9%

반응 조건

후처리

1. 1
   기타This compound was prepared in analogy to Example 52

실험 절차

This compound was prepared in analogy to Example 52, starting from 2-bromo-3-methylthiophene (2.6 g, 15 mmol) and 2-fluoro-5-pyridine-boronic acid (2.3 g, 16.5 mmol, 1.1 equiv.) to obtain 2.2 g of the desired compound as a light yellow oil. MS (ES): m/e 194.2 (M+H)

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