반응 #339341

반응 방정식

6-Methoxybenzo[b]thiophene

pyridine hydrochloride

→

title compound

수율 98.5%

Benzo[b]thiophen-6-ol

수율 98.5%

용매

water

반응 조건

후처리

1. 1
   추출extracted with dichloromethane (3×70 mL)
2. 2
   세척The combined extracts were washed with water (125 mL)
3. 3
   건조dried (MgSO4)
4. 4
   기타evaporated in vacuo

실험 절차

6-Methoxybenzo[b]thiophene (6.15 g, 37.45 mmol) and pyridine hydrochloride (18.5 g) were heated together at 210° C. for 1 h. The mixture was cooled to 100° C., diluted with water (125 mL) and extracted with dichloromethane (3×70 mL). The combined extracts were washed with water (125 mL), dried (MgSO4) and evaporated in vacuo to give the title compound (5.54 g, 98%)

출처