반응 #338896

반응 방정식

3,3′-dibromo-5,5′,7,7′-tetramethyl-1,1′-biadamantane

phenol

→

3,3′-bis(4-hydroxyphenyl)-5,5′,7,7′-tetramethyl-1,1′-biadamantane

수율 99.0%

용매

water

반응 조건

후처리

1. 1
   온도After cooling the mixture to room temperature
2. 2
   workup.STIRRINGagitated at 80° C. for ten minutes
3. 3
   여과Solid precipitate was collected by filtration
4. 4
   세척washed with 7 L of ion-exchange water
5. 5
   기타dried under reduced pressure

실험 절차

In a 5 L recovery flask, 48.4 g of 3,3′-dibromo-5,5′,7,7′-tetramethyl-1,1′-biadamantane (100 mmol), 688 g of phenol (7.3 mol) and a stirrer were charged and agitated at 155° C. for 30 minutes under nitrogen flow. After cooling the mixture to room temperature, 4.3 L of ion-exchange water was added thereto and agitated at 80° C. for ten minutes. Solid precipitate was collected by filtration, then washed with 7 L of ion-exchange water and dried under reduced pressure, thus obtaining 50.6 g of 3,3′-bis(4-hydroxyphenyl)-5,5′,7,7′-tetramethyl-1,1′-biadamantane (99.0 mmol; yield: 99.0%).

출처