반응 #336404

반응 방정식

2-Ethyl-4,5,6,7-tetrahydrobenzimidazole

1-bromo-2-hexyldecane

sodium carbonate

→

1-(2'-hexyldecyl)-2-ethyl-4,5,6,7-tetrahydrobenzimidazole

용매

2-methoxyethanol

반응 조건

후처리

1. 1
   온도heated at 125°-135° C. below a reflux condenser for 15 hours
2. 2
   온도The reaction mixture is cooled
3. 3
   추출extracted with a mixture of toluene (150 parts) and ethyl acetate (50 parts)
4. 4
   세척the extract is washed successively with water, dilute sulphuric acid, dilute sodium hydroxide, and water
5. 5
   workup.DISTILLATIONdistilled

실험 절차

2-Ethyl-4,5,6,7-tetrahydrobenzimidazole (14.3 parts), 2-methoxyethanol (30 parts), 1-bromo-2-hexyldecane (35 parts) and sodium carbonate (5.7 parts) are stirred together and heated at 125°-135° C. below a reflux condenser for 15 hours. The reaction mixture is cooled and extracted with a mixture of toluene (150 parts) and ethyl acetate (50 parts) and the extract is washed successively with water, dilute sulphuric acid, dilute sodium hydroxide, and water, and then distilled yielding 1-(2'-hexyldecyl)-2-ethyl-4,5,6,7-tetrahydrobenzimidazole (V) (16.6 parts), b.p. 185°-200° at 0.2 mm pressure.

출처