반응 #335838
ord-2624c3d956854183a95148f8c3cc395b
반응 방정식
1,4-dichlorobenzene
Dichlorobenzene
3-Toluoyl Chloride
3-toluoyl chloride
AlCl3
aluminum chloride
→
2,5-dichloro-3'-methyl-benzophenone
수율 53.0%
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
The procedure of Example 2 was followed, using 22 ml (0.17 mol) of 3-toluoyl chloride and 60 g (0.45 mol) of aluminum chloride in 120 g (0.82 mol) of 1,4-dichlorobenzene. (The molar ratio of reactants was 2.6:4.8:1.0 (AlCl3 :Dichlorobenzene:3-Toluoyl Chloride)). Pure 2,5-dichloro-3'-methyl-benzophenone was isolated in 53% yield after the crude product was recrystallized twice from hexane.