반응 #335836

ord-a0a6697ef4f34384bc2fb4b978b451d0

반응 방정식

[Al+3].[Cl-].[Cl-].[Cl-]
AlCl3
Clc1ccc(Cl)cc1
1,4-dichlorobenzene
O=C(Cl)c1ccccc1
benzoyl chloride
O=C(c1ccccc1)c1cc(Cl)ccc1Cl
2,5-dichlorobenzophenone
수율 50.0%

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Starting material ratios as low as 1.1/1.3/1 (moles of AlCl3 :1,4-dichlorobenzene:benzoyl chloride) have been found sufficient to produce 2,5-dichlorobenzophenone in about 50% yield under the conditions provided by the present invention; the same ratio of starting materials has been found to give a 64% yield of 2,5-dichlorobenzophenone if the benzoyl chloride is added slowly to a mixture of AlCl3, 1,4-dichlorobenzene and a small amount of benzoyl chloride.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05210313uspto-grants-1993_05