반응 #3357

ord-22175d52cf8d4bbdad038a1e70ab65ca

반응 방정식

NCCCC(=O)O
4-amino-butanoic acid
O=C(Cl)c1ccccc1SSc1ccccc1C(=O)Cl
2,2'-dithiobisbenzoyl chloride
→
O=C(O)CCCNC(=O)c1ccccc1SSc1ccccc1C(=O)NCCCC(=O)O
title compound
수율 49.9%
O=C(O)CCCNC(=O)c1ccccc1SSc1ccccc1C(=O)NCCCC(=O)O
4-[2-[2-(3-Carboxypropylcarbamoyl)phenyldisulfanyl]benzoylamino] butanoic acid
수율 49.9%

반응물

NCCCC(=O)O
4-amino-butanoic acid
O=C(Cl)c1ccccc1SSc1ccccc1C(=O)Cl
2,2'-dithiobisbenzoyl chloride

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Following the procedure in Preparation 30, 16 g (0.15 mol) of 4-amino-butanoic acid was reacted with 10.8 g (0.03 mol) of 2,2'-dithiobisbenzoyl chloride to afford 7.14 g of the title compound.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05733921uspto-grants-1998_03