반응 #335030

ord-5e7f19ff56af4ccabb05d3f49423a133

반응 방정식

CN(CC1CCN(CCCOc2ccc(F)cc2)CC1)S(=O)(=O)c1cccc2cnccc12
compound
CN(CC1CCN(CCCOc2ccc(F)cc2)CC1)S(=O)(=O)c1cccc2cnccc12
N-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamide
CCCl
hydrochloric ether
→
CN(CC1CCN(CCCOc2ccc(F)cc2)CC1)S(=O)(=O)c1cccc2cnccc12.Cl.Cl
title compound
CN(CC1CCN(CCCOc2ccc(F)cc2)CC1)S(=O)(=O)c1cccc2cnccc12.Cl.Cl
N-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamide dihydrochloride

반응물

—
solid
CN(CC1CCN(CCCOc2ccc(F)cc2)CC1)S(=O)(=O)c1cccc2cnccc12
compound
CN(CC1CCN(CCCOc2ccc(F)cc2)CC1)S(=O)(=O)c1cccc2cnccc12
N-Methyl-N-{[1-[3-(p-fluorophenoxy)propyl]-4-piperidyl]methyl}-5-isoquinolinesulfonamide
—
solution
CCCl
hydrochloric ether

시약

없음

용매

CC#N
acetonitrile

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

5.5 g of the compound obtained in stage A is taken up in 10 cm3 of acetonitrile. 7.5 cm3 of a 3.3N solution of hydrochloric ether are added to this solution. 3.1 g of a solid which corresponds to the title compound are obtained.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05208243uspto-grants-1993_05