반응 #332697

반응 방정식

benzylamine

1,2-epoxybutane

→

1-benzylamino-butan-2-ol

용매

ethanol

반응 조건

후처리

1. 1
   농축It was concentrated
2. 2
   workup.DISTILLATIONdistilled at 140-150° C./2 mm Hg
3. 3
   기타to give product as color less liquid, which
4. 4
   기타slowly crystallizes at room temperature after 2 days

실험 절차

To a solution of benzylamine (29.65 g, 277.0 mmol) in ethanol (40 mL) was added 1,2-epoxybutane (4 g, 55.47 mmol) and the mixture was heated to 150° C. for 2 h in a autoclave. It was concentrated and distilled at 140-150° C./2 mm Hg to give product as color less liquid, which slowly crystallizes at room temperature after 2 days. Yield: 8.5 g (85%)

출처