반응 #331844

반응 방정식

methyl 2-amino-5-(1-methylethyl)-1,3-thiazole-4-carboxylate

hydrochloric acid

→

title compound

수율 117.3%

2-Amino-5-(1-methylethyl)-1,3-thiazole-4-carboxylic acid

수율 117.3%

용매

1,4-dioxane

반응 조건

후처리

1. 1
   기타The mixture was evaporated in vacuo

실험 절차

To a solution of methyl 2-amino-5-(1-methylethyl)-1,3-thiazole-4-carboxylate (220 mg) (for example, available from ABCR) in 1,4-dioxane (5 ml) was added 2M hydrochloric acid (5 ml) and the mixture heated at 110° C. for 72 h. The mixture was evaporated in vacuo to give the title compound (240 mg) as a pale yellow solid.

출처