반응 #331482

반응 방정식

compound

5,6-dibromo-2,2-dimethylhexahydro-1,3-benzodioxol

DBU

→

2,2-dimethyl-3a,7a-dihydrobenzo[1.3]dioxol

용매

toluene

반응 조건

후처리

1. 1
   온도the mixture was refluxed for 6 hours
2. 2
   여과After the reaction product had been filtrated
3. 3
   workup.ADDITIONsodium hydrogen carbonate was added to the filtrate
4. 4
   건조the organic layer was dried over magnesium sulfate

실험 절차

The compound obtained in Step (11) was placed in a reaction vessel, and air in the vessel was replaced with nitrogen. After that, the compound was dissolved in dehydrated toluene (116 ml). Distilled DBU (6.0 ml, 40.1 mmol) was added to the solution, and the mixture was refluxed for 6 hours. After the reaction product had been filtrated, sodium hydrogen carbonate was added to the filtrate, and the organic layer was dried over magnesium sulfate, whereby 2,2-dimethyl-3a,7a-dihydrobenzo[1.3]dioxol was obtained. The compound was used in the next reaction without being further purified.

출처