반응 #328913

반응 방정식

compound

3-Methylsulphanyl-2-oxo-2,3-dihydro-1H-indole-5-carbonitrile

→

title product

2-Oxo-2,3-dihydro-1H-indole-5-carbonitrile

용매

THF

THF

반응 조건

후처리

1. 1
   여과The reaction mixture is then filtered over a bed of Celite
2. 2
   기타evaporated to dryness

실험 절차

To a suspension of Raney nickel in THF (100 ml) there is added the compound obtained in Step A (20 mmoles) dissolved in THF (400 ml). The reaction mixture is stirred at ambient temperature until the starting material has completely disappeared. The reaction mixture is then filtered over a bed of Celite and then evaporated to dryness to yield the title product, which is used directly in the next reaction.

출처