반응 #323846

반응 방정식

α-oxo-2-nitrobenzenepropanoic acid

sodium borohydride

hydrochloric acid

→

titled product

α-Hydroxy-2-Nitrobenzenepropanoic Acid

용매

water

반응 조건

후처리

1. 1
   온도to maintain a temperature between 45° and 50°
2. 2
   온도cooling
3. 3
   기타gave crude product
4. 4
   기타Recrystallization from water

실험 절차

To a magnetically stirred suspension of α-oxo-2-nitrobenzenepropanoic acid (5.00 g) in water (75 ml) containing 1 drop of decyl alcohol was added sodium borohydride (2.50 g) in portions to maintain a temperature between 45° and 50°. The resulting solution was then left at room temperature for 21/2 hours. The solution was acidified with concentrated hydrochloric acid and seeded. Stirring and cooling gave crude product; yield 5.01 g, m.p. 84°-90°. Recrystallization from water gave titled product; yield 2.63 g (52%), m.p. 95°-98° with spectral data as above.

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