반응 #323068

ord-4716f022c44b4bc49d48c338ed1f34ea

반응 방정식

O=C(O)Cc1nc(-c2ccc(Cl)cc2)oc1-c1ccco1
2-[2-(4-chlorophenyl)-5-(2-furyl)-4-oxazolyl]acetic acid
C[n+]1ccccc1Cl.[I-]
2-chloro-1-methylpyridinium iodide
CCCCCCCCCCCCO
laurylalcohol
CCN(CC)CC
triethylamine
CCCCCCCCCCCCOC(=O)Cc1nc(-c2ccc(Cl)cc2)oc1-c1ccco1
lauryl 2-[2-(4-chlorophenyl)-5-(2-furyl)-4-oxazolyl]acetate
수율 77.4%

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

2.0 g of 2-[2-(4-chlorophenyl)-5-(2-furyl)-4-oxazolyl]acetic acid, 2.02 g of 2-chloro-1-methylpyridinium iodide, 1.47 g of laurylalcohol, 1.60 g of triethylamine and 60 ml of tetrahydrofuran are treated in the same manner as described in Example 27. 2.4 g of lauryl 2-[2-(4-chlorophenyl)-5-(2-furyl)-4-oxazolyl]acetate are obtained. Yield: 77.4%

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04642313uspto-grants-1987_02