반응 #321543

반응 방정식

2-benzylthiophene

chlorosulfonic acid

→

5-benzylthiophene-2-sulfonic acid

용매

chloroform

반응 조건

후처리

1. 1
   workup.ADDITIONby pouring
2. 2
   추출The mixture was extracted with ethyl acetate
3. 3
   건조dried over MgSO4
4. 4
   여과filtered
5. 5
   기타The solvent was removed under reduced pressure

실험 절차

To a solution of 2-benzylthiophene (0.875 g, 5 mmol) in chloroform (2 ml) at 0° C. was added chlorosulfonic acid dropwise and the reaction was stirred at 0° C. for 30 min. The reaction mixture was decomposed by pouring onto crushed ice (20 g). The mixture was extracted with ethyl acetate, dried over MgSO4 and filtered. The solvent was removed under reduced pressure to give 5-benzylthiophene-2-sulfonic acid.

출처