반응 #3208

반응 방정식

6-methoxy-2-nitrobenzoic acid

→

benzoic acid

수율 100.2%

2-amino-6-methoxybenzoic acid

수율 100.2%

용매

ethanol

반응 조건

후처리

1. 1
   기타When hydrogen consumption
2. 2
   여과the resulting mixture was filtered through diatomaceous earth
3. 3
   농축the filtrate concentrated

실험 절차

A solution of 6-methoxy-2-nitrobenzoic acid (3.25 g, 16.5 mM) in ethanol (180 mL) containing 10% palladium-on-carbon catalyst (0.30g) was hydrogenated using a Parr apparatus. When hydrogen consumption ceased, the resulting mixture was filtered through diatomaceous earth and the filtrate concentrated to provide the title benzoic acid (2.76 g, 100%) as a tan solid; MS(CI): 168 (M+H).

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