반응 #319290

반응 방정식

hydrogen

water

compound

1-[6-(4-methoxyphenyl)hex-5-enyl]imidazole, hydrochloride

sodium bicarbonate

→

title compound

1-[6-(4-methoxyphenyl)hexyl]imidazole

용매

ethanol

반응 조건

후처리

1. 1
   기타Partition with water/methylene chloride
2. 2
   세척Elute on a silica column with 100% methylene chloride

실험 절차

Add 1 ml water to 400 mg of the compound prepared in Example 72, then add 100 mg sodium bicarbonate followed by 25 ml ethanol. Add 100 mg PtO and add hydrogen under 30 psi for 20 hr. Partition with water/methylene chloride. Elute on a silica column with 100% methylene chloride then 5% methanol/methylene chloride to yield the title compound.

출처