반응 #318856

반응 방정식

barium sulfate

2,4-difluorobenzoylchloride

→

2,4-difluorobenzaldehyde

용매

decahydronaphthalene

반응 조건

후처리

1. 1
   기타The reaction was purged with H2 for 0.25 hour
2. 2
   workup.ADDITIONHydrogen was dispersed through the system for 6 hours

실험 절차

30 ml (27 g) of decahydronaphthalene and 0.5 g (2.3×10-4 ml) of a catalyst of 5% palladium on a barium sulfate support were added to the flask containing the 2,4-difluorobenzoylchloride. The reaction was purged with H2 for 0.25 hour, then the temperature was raised to 130° C. Hydrogen was dispersed through the system for 6 hours. The product 2,4-difluorobenzaldehyde was isolated as a colorless liquid. Yield 9.8 g (82%).

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