반응 #318449

반응 방정식

12-cyclohexyldodecanol

epichlorohydrin

sodium hydroxide

→

captioned compound

수율 71.2%

1,2-Epoxy-3-(12-cyclohexyldodecyloxy)propane

수율 71.2%

용매

toluene

반응 조건

후처리

1. 1
   기타The resulting reaction mixture
2. 2
   세척is then washed with water
3. 3
   기타dried
4. 4
   농축concentrated
5. 5
   기타to leave a residue which in turn
6. 6
   기타is purified by silica gel chromatography

실험 절차

A mixture containing 26.5 g of 12-cyclohexyldodecanol, 27.4 g of epichlorohydrin, 52.6 g of a 50% aqueous sodium hydroxide solution, 2.0 g of cetyltrimethylammonium chloride and 300 ml of toluene is stirred at 60° C. for 24 hours. The resulting reaction mixture is then washed with water, dried and concentrated to leave a residue which in turn is purified by silica gel chromatography to obtain 22.8 g of the captioned compound as a colorless oily substance.

출처