반응 #318320

반응 방정식

4-bromo-3-methylaniline

p-toluenesulfonyl isocyanate

→

title product

수율 80.0%

N-([(4-bromo-3-methylphenyl)amino]carbonyl)-4-methylbenzenesulfonamide

수율 80.0%

용매

toluene

methylene chloride

toluene

methylene chloride

반응 조건

후처리

1. 1
   여과filtered

실험 절차

A solution of 5.58 g of 4-bromo-3-methylaniline in 20 ml of toluene and 5 ml of methylene chloride was added to a solution of 5.91 g of p-toluenesulfonyl isocyanate in 50 ml of toluene and 10 ml of methylene chloride under a nitrogen atmosphere. The mixture was stirred overnight and filtered, providing 9.19 g of the title product, m.p. 178°-180° C.

출처