반응 #314574

ord-ed571ac63d0c4329805ce0dbf15561d7

반응 방정식

OCCCN1CCOCC1
4-(3-hydroxypropyl)morpholine
CCN(CC)CC
triethylamine
CS(=O)(=O)Cl
methanesulfonyl chloride
CS(=O)(=O)OCCCN1CCOCC1
title compound
CS(=O)(=O)OCCCN1CCOCC1
3-morpholin-4-ylpropyl methanesulfonate

용매

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The 4-(3-hydroxypropyl)morpholine (Aldrich, 0.18 g, 1.2 mmol), triethylamine (0.56 mL, 4.1 mmol), and methanesulfonyl chloride (0.15 mL, 1.9 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07560481B2uspto-grants-2009_07