반응 #313790

반응 방정식

ethyl 4-nitrophenoxyacetate

→

ethyl 4-aminophenoxyacetate

용매

EtOH

반응 조건

후처리

1. 1
   여과After the filtration through a celite the solvent
2. 2
   기타was removed under a reduced pressure

실험 절차

A solution of ethyl 4-nitrophenoxyacetate (15 g) in EtOH (400 mL) was hydrogenated at 40 PSI for 40 minutes in the presence of 10% Pd/C (1.5 g, 10% by weight). After the filtration through a celite the solvent was removed under a reduced pressure to obtain ethyl 4-aminophenoxyacetate. 1H NMR (CDCl3): δ 6.77 (d, 2H, 8.1 GHz), 6.60 (d, 2H, J=8.0 Hz), 4.50 (s, 2H), 4.24 (q, 2H), 1.24 (t, 3H); LCMS: ret. time: 12.00 min.; purity: 100%; MS (m/e): 196 (MH+).

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