반응 #313131

반응 방정식

compound

t-butyl (3S)-3-{[(5-methyl-3-phenyl-4,5-dihydro-5-isoxazolyl)carbonyl]amino}-4-oxo-5-phenoxypentanoate

trifluoroacetic acid

→

title compound

수율 99.7%

(3S)-3-{[(5-methyl-3-phenyl-4,5-dihydro-5-isoxazolyl)carbonyl]amino}-4-oxo-5-phenoxypentanoic Acid

수율 99.7%

용매

dichloromethane

반응 조건

후처리

1. 1
   농축concentrated under reduced pressure

실험 절차

The compound prepared in Example 3 (530 mg, 1.136 mmol) was dissolved in dichloromethane (6 ml), and trifluoroacetic acid (3 ml) was added at 0□. The mixture was stirred for two hours while it was slowly warmed to room temperature, and concentrated under reduced pressure to give the title compound (Ibb) (465 mg) with a stoichiometric yield.

출처