반응 #313129

반응 방정식

compound

(3S)-5-(t-butoxy)-3-{[(5-methyl-3-phenyl-4,5-dihydro-5-isoxazolyl)carbonyl]amino}-2,5-dioxopentyl 2,6-dichlorobenzoate

trifluoroacetic acid

→

title compound

(3S)-5-[(2,6-dichlorobenzoyl)oxy]-3-{[(5-methyl-3-phenyl-4,5-dihydro-5-isoxazolyl)carbonyl]amino}-4-oxopentan-oic acid

용매

dichloromethane

반응 조건

후처리

1. 1
   농축concentrated under reduced pressure

실험 절차

The compound prepared in Example 1 (44 mg) was dissolved in dichloromethane (2 ml), and trifluoroacetic acid (1 ml) was added at 0□. The mixture was stirred for two hours while it was slowly warmed to room temperature, and then concentrated under reduced pressure to give the title compound (Iaa) in a stoichiometric amount.

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