반응 #312409

반응 방정식

triethylamine

2,2-dimethyl thiazolidine

benzene

dibromoacetyl chloride

→

2,2-dimethyl-3-dibromoacetyl thiazolidine

용매

water

반응 조건

후처리

1. 1
   workup.ADDITIONTo a mixture of 3.5 g
2. 2
   workup.ADDITIONwas added 3.1 g
3. 3
   온도continued cooling
4. 4
   기타When reaction
5. 5
   기타the benzene layer separated
6. 6
   건조dried over magnesium sulfate
7. 7
   기타the benzene removed under vacuum

실험 절차

To a mixture of 3.5 g. of 2,2-dimethyl thiazolidine, 50 ml. of benzene and 7.1 g. of dibromoacetyl chloride mixed in an ice bath was added 3.1 g. of triethylamine dropwise with stirring and continued cooling. When reaction was complete, the mixture was poured into water and the benzene layer separated, dried over magnesium sulfate and the benzene removed under vacuum. Yield was 8.5 g. of a dark oil.

출처