반응 #309604

반응 방정식

Benzylbromide

diethyl 1,4-dihydroxy-2,3-naphthalenedicarboxylate

potassium carbonate

→

title compound

수율 109.4%

Diethyl 1,4-bis[(phenylmethyl)oxy]-2,3-naphthalenedicarboxylate

수율 109.4%

용매

acetone

반응 조건

후처리

1. 1
   온도The reaction mixture was refluxed for 18 hours under an atmosphere of argon
2. 2
   기타The resulting mixture was evaporated
3. 3
   기타the reaction mixture triturated with water
4. 4
   여과was collected by filtration
5. 5
   세척washed with water
6. 6
   기타then dried under vacuum

실험 절차

Benzylbromide (2.95 ml, 24.7 mmol) was added to a stirred solution of diethyl 1,4-dihydroxy-2,3-naphthalenedicarboxylate (3 g, 9.87 mmol) and potassium carbonate (3.40 g, 24.7 mmol) in acetone (100 ml). The reaction mixture was refluxed for 18 hours under an atmosphere of argon. The resulting mixture was evaporated and the reaction mixture triturated with water. The resulting tan coloured solid was collected by filtration and washed with water then dried under vacuum to give the title compound (5.23 g, 10.8 mmol). LC/MS: Rt=4.13, [MH]+ 485.

출처