반응 #307520
ord-7db65914d01d4f049bfc3bd1369acb02
반응 방정식
isoniazid
streptomycin
ethambutol
Pyrazinamide
rifampicin
→
isoniazid
streptomycin
ethambutol
SQ109
용매
반응 조건
온도
-80°CELSIUS
상세 조건
See reaction.notes.procedure_details.
후처리
- 1workup.DISTILLATIONin distilled
- 2여과deionized water at 10 mg/mL, sterilized by filtration
- 3기타Stock solutions of rifampicin, at 1 or 10 mg/mL, were prepared in methanol
- 4기타stored at −80° C
- 5기타, and a stock solution was prepared
- 6기타stored at 80° C.
실험 절차
Antimicrobial drugs isoniazid, rifampicin, streptomycin, and ethambutol were purchased from Sigma-Aldrich. St. Louis, Mo. Stock solutions of isoniazid, streptomycin, and ethambutol were prepared in distilled and deionized water at 10 mg/mL, sterilized by filtration, and stored frozen at −80° C. Stock solutions of rifampicin, at 1 or 10 mg/mL, were prepared in methanol and stored at −80° C. Pyrazinamide was purchased as the drug reconstituting kit from Becton Dickinson, Cockeysville, Md., and a stock solution was prepared following instructions by the manufacturer. Stock solutions of SQ109 were prepared in methanol at 1 mg/mL and stored at 80° C.