반응 #3071

반응 방정식

3-bromo-4-fluorobenzaldehyde

DMF

triethylamine

MeOH

→

methyl 3-carbomethoxy-4-fluorobenzaldehyde

반응 조건

후처리

1. 1
   추출Extraction and chromatography

실험 절차

A mixture of 1.0 mmol of 3-bromo-4-fluorobenzaldehyde, 4 mL of DMF, 0.2 mL of triethylamine, 0.4 mL of MeOH and 0.05 mmol of Pd(PPh3)4 was heated at 90° C. at 40 psi under CO atmosphere for 16 h. Extraction and chromatography provided methyl 3-carbomethoxy-4-fluorobenzaldehyde.

출처